Custom Antibody Technology
Cellstate Biosciences builds custom ICC, IHC, and ELISA immunoassays.
Our antibody design technology and dye labeling techniques allow for multiplexing of bright and highly target-specific antibodies for readily quantifiable data.
Plex-mAb Antibodies
The next generation of fluorescently labeled antibodies for ICC, IHC, and ELISA.
Plex-mAb Antibodies represent our innovative leap in immunolabeling technology. Purpose-built for enhanced assay performance, these primary labeled antibodies sidestep the complications commonly associated with standard immunoassays. Traditional methods often rely on secondary or tertiary systems for primary antibody detection, which can restrict multiplexing applications and introduce issues like cross-reactivity between antibodies from related species.
By re-engineering the antibody incorporation process, Plex-mAb Antibodies achieve optimal dye and conjugate integration. This process is finely tuned to preserve the strong and specific binding affinity—avidity—of the antibody to its target, ensuring clear and precise labeling in your assays.
The real-world performance of Plex-mAb Antibodies frequently matches or surpasses that of traditional primary plus secondary antibody systems. This advancement not only expedites assay throughput but also substantially diminishes the risk of ambiguous results often encountered with conventional methods.
Image: Comparison of commercially available direct ICC (Vendor ‘A’), indirect ICC (Vendor ‘C’ plus a Secondary antibody), and direct ICC with Cellstate Biosciences Plex-mAb Antibody. All antibodies are anti-Her2. SKBR3 cells are HER2 overexpressing (+++) and MDA-MB-231 cells are Her2 no/low expressing (-/+).
Plex-mAb Multiplex Assays
Revolutionizing ICC and IHC Imaging for Comprehensive Analysis.
Harnessing the power of our proprietary Plex-mAb Antibodies, we've pioneered a suite of custom multiplex assays that redefine the scope of immunocytochemistry (ICC) and immunohistochemistry (IHC). Our approach utilizes spectrally distinct dyes, each meticulously chosen for its ability to cleanly separate signals, enabling precise labeling of multiple targets. This spectral separation allows for simultaneous detection and quantification of various biomarkers within the same sample, providing a layered, in-depth analysis that was once thought to be unachievable in a single run.
By integrating these advanced assays into your workflow, you can:
Visualize multiple cellular targets concurrently, preserving the integrity of your sample.
Obtain a comprehensive biomarker profile from a single tissue section or cell culture, maximizing your data while minimizing sample consumption.
Enhance the efficiency of your research by reducing the need for multiple assays, saving both time and resources.
Our Plex-mAb Multiplex Assays are not just a step forward; they are a leap into a new era of imaging where clarity meets depth, bringing the unseen details of cellular interactions into focus.
Expanded Multiplex Assays
Unlocking New Dimensions in Multiplexing with Cyclic ICC
At Cellstate Biosciences, we’ve pushed the frontiers of multiplex immunoassays by devising novel cyclic ICC methods. Central to this innovation is our development of a unique class of cleavable dyes, designed for seamless detachment and reapplication in successive imaging cycles. This breakthrough allows for unprecedented levels of multiplexing, making it simpler than ever to perform comprehensive immunoassays with our advanced Illuminator Antibodies. Now, you can interrogate a vast array of biomarkers in a single sample, unveiling intricate biological processes with unparalleled clarity and convenience.
Direct ELISA Antibodies
Enhanced Sensitivity for High-Performance ELISAs
Leverage the precision of Cellstate's custom Plex-mAb Antibodies in your direct ELISA applications. Engineered for heightened sensitivity, our antibodies enable you to detect even low-abundance analytes with confidence. Plus, our innovative approach supports multiplex ELISA formats, allowing simultaneous quantification of multiple targets without compromising accuracy or reliability. Optimize your assays with our technology and gain comprehensive insights with each ELISA run.
